Journal of Biomedical and Clinical Research 17(2): 187-196, doi: 10.3897/jbcr.e121855

Relationship between Child-Pough score and late complications in hospital patients with liver cirrhosis

Miroslava Mihailova-Strashilova^‡, Pencho Tonchev^‡§

‡ Medical University – Pleven, Pleven, Bulgaria§ Univeristy Hospital “G. Stransky”, Pleven, Bulgaria

Corresponding author: Miroslava Mihailova-Strashilova ( mihailova75.md@gmail.com )

Academic editor: Zornitsa Gorcheva

This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Citation: Mihailova-Strashilova M, Tonchev P (2024) Relationship between Child-Pough score and late complications in hospital patients with liver cirrhosis. Journal of Biomedical and Clinical Research 17(2): 187-196. https://doi.org/10.3897/jbcr.e121855

Abstract

This study aimed to determine the frequency of available complications in patients with liver cirrhosis and any dependence according to the Child-Pough score. A retrospective study of cases with newly diagnosed liver cirrhosis was conducted in the Gastroenterology Clinic of UMBAL Pleven from 2017 to 2021. Of them, 258 (71.5%) were men and 103 (28.5%) were women. The mean age of the studied population was 57.8 years ± 11.4 years. The leading aetiology was alcohol in 244 (67.6%) of them. All cases were classified according to Child-Pough score system into three groups: Child A 98(27%), Child B 141(39%), and Child C 122(34%). Ours findings show that the occurrence of ascites is most common in the studied population at 232 (64.5%). Esophageal varices were found in 164 (62.4%) patients out of 264 who underwent upper gastrointestinal endoscopy. Portal encephalopathy was found in 170 (47.09%), with a predominance of the minimal in 116 (68.23%) of them. Jaundice was found in 124 (34.34%), and more of them were in Child C. In 65 (18%), renal dysfunction was found, such as acute renal dysfunction in 12.4%. In conclusion, the high frequency of available complications is closely related to late diagnosis.

Keywords

Child-Pough, complications, liver cirrhosis