Journal of Biomedical and Clinical Research 6(2): 89-93, doi: 10.1515/jbcr-2015-0107
Abnormal Levels of Inflammatory and Oxidative Stress Markers in Patients with Arterial Hypertension and Diabetes Mellitus
Maya Danovska‡, Margarita L. Alexandrova, Irena I. Gencheva‡ MD, PhD, Pleven, Bulgaria
© Maya Danovska, Margarita Alexandrova, Irena Gencheva. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY-NC-ND 4.0), which permits to copy and distribute the article for non-commercial purposes, provided that the article is not altered or modified and the original author and source are credited. Citation:
Danovska M, Alexandrova ML, Gencheva II (2013) Abnormal Levels of Inflammatory and Oxidative Stress Markers in Patients with Arterial Hypertension and Diabetes Mellitus. Journal of Biomedical and Clinical Research 6(2): 89-93. https://doi.org/10.1515/jbcr-2015-0107 |  |
Abstract
Individuals with hypertension and diabetes mellitus are at high risk of cerebrovascular and cardiovascular morbidity and mortality. Recent advances in the multifactorial pathophysiology of atherogenesis provide important information about the complex interrelations between traditional risk factors, inflammation and oxidative stress in mediating all stages of atherosclerosis. The objective of the study was to determine if some inflammatory and oxidative stress markers in patients with arterial hypertension and diabetes mellitus differ from those in healthy age-matched controls. Our results revealed a significant difference in blood pro/antioxidant activities in hypertensive diabetics and the controls. The investigation of inflammatory and oxidative stress markers along with traditional risk factors proves useful in complex assessment of vascular risk and primary prophylaxis of cerebrovascular and cardiovascular events.
Keywords
diabetes, hypertension, inflammation, oxidative stress, C-reactive protein