Journal of Biomedical and Clinical Research 8(1): 19-25, doi: 10.1515/jbcr-2015-0146
Translation, Adaptation And Validation Of The Bulgarian Version Of The SIDAED Questionnaire
expand article infoRumyana N. Kuzmanova, Irina Z. Stefanova, Irena V. Velcheva, Katerina I. Stambolieva
© Rumyana Kuzmanova, Irina Stefanova, Irena Velcheva, Katerina Stambolieva.
This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY-NC-ND 4.0), which permits to copy and distribute the article for non-commercial purposes, provided that the article is not altered or modified and the original author and source are credited.
Citation: Kuzmanova RN, Stefanova IZ, Velcheva IV, Stambolieva KI (2015) Translation, Adaptation And Validation Of The Bulgarian Version Of The SIDAED Questionnaire. Journal of Biomedical and Clinical Research 8(1): 19-25. https://doi.org/10.1515/jbcr-2015-0146
Open Access
Abstract
The aim of the study is the translation, adaptation and validation of Side effects of antiepileptic drugs questionnaire in Bulgarian language (SIDAED-BG) in order to use it for objective monitoring of patients with epilepsy. One hundred and thirty one patients (mean age 40.13±13.37 years) took part in the investigation. The internal consistency and test-retest reliability were tested by Cronbach's α and ICC estimations. The convergent construct validity was evaluated by estimating the correlation of SIDAED-BG with the QOLIE-89 and the discriminant validity - by evaluation of the difference between SIDAED-BG scores and clinical parameters such as type of epilepsy using Kruskal-Wallis ANOVA. The Cronbach's α of the total scale was 0.93. The test-retest reliability was higher and determined the strong positive correlations between the first and second examination. The SIDAED-BG questionnaire showed good internal consistency (Cronbach's alpha ranged from 0.37 to 0.86) and the scores significantly correlated with other questionnaires such as QOLIE-89 and showed a good discriminative validity between groups with different levels of self-assessed adverse effects of antiepileptic drugs. The Bulgarian version of SIDAED is a reliable and valid tool in assessing the patient-reported adverse effects of antiepileptic drugs and their impact on the patient's outcome.
Keywords
SIDAED questionnaire, epilepsy, adverse events, antiepileptic treatment, quality of life in epilepsy inventory