Journal of Biomedical and Clinical Research 8(1): 30-34, doi: 10.1515/jbcr-2015-0148
Multivessel Disease As A Prognostic Factor For Mortality In STEMI Patients
Kiril K. Karamfiloff, Kiril Karamfilov Karamfiloff‡, Petya G. Georeva, Diana K. Trendafilova, Julia B. Jorgova‡ UMHAT Alexandrovska, Sofia, Bulgaria
© Kiril Karamfiloff, Kiril Karamfiloff, Petya Georeva, Diana Trendafilova, Julia Jorgova. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY-NC-ND 4.0), which permits to copy and distribute the article for non-commercial purposes, provided that the article is not altered or modified and the original author and source are credited. Citation:
Karamfiloff KK, Karamfiloff K, Georeva PG, Trendafilova DK, Jorgova JB (2015) Multivessel Disease As A Prognostic Factor For Mortality In STEMI Patients. Journal of Biomedical and Clinical Research 8(1): 30-34. https://doi.org/10.1515/jbcr-2015-0148 |  |
Abstract
The main objective of this analysis was to define the influence of multivessel disease involvement compared to single vessel disease on mortality rates in STEMI patients. The retrospective study included 549 patients, hospitalized with STEMI in St. Ekaterina University Hospital (age - 62.66±12.56; women - 31.3%) from 01.06.2008 to 30.06.2011. One-vessel disease was found in 232 patients (44%) as compared to two-vessel disease in 165 patients - 31% and multivessel disease in 130 patients - 25%. There was LM stenosis (>30) in 11 patients (2%); ostial lesion in 33 patients (6.3%); presence of Ca in 37 patients (7%). A stent was implanted in 484 patients (91.8%), and GP IIb/IIIa was used in 400 patients (75.9%). There was significant increase in mortality rates in patients with multivessel disease: 15.6% - 46 patients, compared to one-vessel disease - 6.5% (15 patients) (p<=0.01). Both early (30 days) and late mortality (one year) rates were higher in the multivessel group (6.8% vs. 2.6%, p<=0.05 and 10.2% vs. 3.9% (p<=0.0510), respectively. Multivessel disease is associated with higher mortality rates in STEMI patients, which may further alter clinical course and decision making.
Keywords
STEMI, mortality, multi-vessel disease