Journal of Biomedical and Clinical Research 11(1): 36-40, doi: 10.2478/jbcr-2018-0006
Clinical Aspects of Food Allergy in Infants in Pleven Region, Bulgaria
Vanya M. Nedkova-Milanova, Tsvetelina V. Miteva, Darina N. Hristova, Lyubomira D. Gadjelova, Magdalena I. Balashkova© Vanya Nedkova-Milanova, Tsvetelina Miteva, Darina Hristova, Lyubomira Gadjelova, Magdalena Balashkova. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY-NC-ND 4.0), which permits to copy and distribute the article for non-commercial purposes, provided that the article is not altered or modified and the original author and source are credited. Citation:
Nedkova-Milanova VM, Miteva TV, Hristova DN, Gadjelova LD, Balashkova MI (2018) Clinical Aspects of Food Allergy in Infants in Pleven Region, Bulgaria. Journal of Biomedical and Clinical Research 11(1): 36-40. https://doi.org/10.2478/jbcr-2018-0006 |  |
Abstract
Food allergy is an immunoglobulin E-meditated reaction, to which the organism’s immune system reacts to a food allergen, recognizing it as harmful. The study aimed to establish at what age cow’s milk protein allergy is manifested and determine the values of immunoglobulin E (IgE) and hemoglobin(Hb) in children with CMPA in Pleven region, Bulgaria. The study included 94 infants presenting with clinical manifestations of food allergy (age range 0 to 12 months) from Pleven and Pleven region, consulted in 2017 by a pediatrician at the University Hospital Consulting Center in Pleven. Venous blood was collected to determine the IgE and Hb values. Chronic iron-deficiency anemia could be the only clinical manifestation in children with CMPA. Out of all the children with CMPA, 17% had a pronounced anemic syndrome. The rest had normal Hb values. Anemic syndrome could have severe consequences for a growing child. Elevated IgE values were found in 73% of the children tested. CMPA is frequently seen in infants. Early diagnosis of clinical manifestations and diet could prevent severe complications of allergy such as chronic diarrhea, chronic urticaria, and asthma.
Keywords
food allergy, clinical manifestation, infants